Jeremy R. Knowles
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|Jeremy R. Knowles|
|Born||April 28, 1935|
|Died||April 3, 2008(aged 72)|
|Doctoral students||Hagan Bayley|
|Known for||Enzyme catalysis|
Jeremy Randall Knowles, CBE, FRS (April 28, 1935 – April 3, 2008) was a professor of chemistry at Harvard University, was Dean of the Harvard University Faculty of Arts and Sciences from 1991 to 2002. He joined Harvard in 1974, received many awards for his research, and remained at Harvard until his death, leaving the faculty for a decade to serve as Dean. Knowles died on April 3, 2008 at his home.
In 2006, he was selected by incoming interim president Derek Bok to return to his position as Dean of the Faculty of Arts and Sciences on an interim basis, replacing William C. Kirby, who was ousted by now former president Lawrence Summers.
Life and work
Knowles was born in England in 1935, educated at Magdalen College School, Oxford and Balliol College, Oxford (BA 1959, DPhil 1961). He was a Pilot Officer in the Royal Air Force. He later became Fellow and Tutor at Wadham College, Oxford, took a post-doctoral fellowship at California Institute of Technology, and was a visiting professor at Yale. He then became a Sloan visiting professor at Harvard, and then a permanent professor there.
Knowles's research was on the boundary of chemistry and biochemistry, and concerned the rate and specificity of enzyme catalysis and the evolution of protein function. He was the author of more than 250 research papers, and advised more than 50 Ph.D. recipients at Oxford and at Harvard, including Hagan Bayley and Ronald T. Raines.
Knowles married Jane Sheldon Davis in 1960, and they had three sons.
Awards and honors
Knowles was a Fellow of the Royal Society, the American Academy of Arts and Sciences, the American Philosophical Society, the American Association for the Advancement of Science, and a Foreign Associate of the National Academy of Sciences. Among his awards are the Royal Society of Chemistry's Charmian Medal, the Bader Award, the Repligen Corporation Award in Chemistry of Biological Processes, the Prelog Medal, the Robert A. Welch Award in Chemistry, the American Chemical Society's Arthur Cope Scholar Award, and the Nakanishi Prize. He was awarded the Davy Medal of the Royal Society, and was an Honorary Fellow of Balliol College and of Wadham College, Oxford. He held honorary degrees from the University of Edinburgh and the Eidgenössische Technische Hochschule in Zürich. He was appointed CBE in the Queen's Birthday Honours of 1993. He was elected one of nine Trustees of the Howard Hughes Medical Institute in 1998.
- Bayley, H.; Knowles, J. R. (1978). "Photogenerated reagents for membrane labeling. 2. Phenylcarbene and adamantylidene formed within the lipid bilayer". Biochemistry 17 (12): 2420–2423. PMID 678520.
- Raines, R. T. (2008). "Jeremy R. Knowles (1935−2008)". ACS Chemical Biology 3 (5): 262–264. doi:10.1021/cb800099n. PMID 18484705.
- Jeremy R. Knowles named Interim Dean of the Faculty of Arts and Sciences, Harvard University Gazette, published 2006-05-22; retrieved 2009-06-10.
- HHMI bio
- Bio from Harvard (from the office of news and public affairs)
- Public biography
- Harvard Crimson Profile
- Harvard Gazette Obituary
- Daily Telegraph Obituary