Carcopino was born at Verneuil-sur-Avre, Eure and educated at the École Normale Supérieure where he specialised in history. From 1904 to 1907 he was a member of the French School in Rome. In 1912 he was a professor of history in Le Havre. In 1912 he became a lecturer at the University of Algiers and inspector of antiquities in Algeria until 1920. His career was interrupted by World War I when he served in the Dardanelles. He became a professor at the Sorbonne in 1920 until 1937 when he became Director of the French School in Rome. From 25 February 1941 to 18 April 1942 he was the Minister of National Education and Youth in the government of Vichy France. He was a member of many archaeological and historical institutes in Europe.
Jérôme Carcopino (1924). Points de vue sur l'ìmpérialisme romain.
Jérôme Carcopino (1940). La vie Quotidienne à Rome à l’Apogée de l’Empire. (English: Daily Life in Ancient Rome: The People and the City at the Height of the Empire. Ed. Henry T. Rowell. Trans. Emily Overend Lorimer. Yale University Press. ISBN0-300-00031-6.
Jérôme Carcopino (1951). Cicero: The Secrets of His Correspondence. Routledge & Kegan Paul Ltd.
Jérôme Carcopino (1961). Les Etapes de l'impérialisme romain.