Jimmy "Duck" Holmes (born 1947) is an American blues musician and proprietor of the Blue Front Cafe on the Mississippi Blues Trail.
He was born to Carey and Mary Holmes, who were sharecroppers. His parents opened the Blue Front Cafe the year after he was born. They had ten children, but also raised four grandchildren when one of their daughters died.
Holmes was influenced by Jack Owens, who is part of the Bentonia School of blues musicians. He is one of the oldest active purveyors of the country blues tradition.
He was recorded by several people, including Alan Lomax during the 1970s, but did not release his first album until 2006 on the Broke and Hungry label.