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Jintropin is produced at Genescience Pharmaceuticals by recombinant DNA technology in E. coli secretion expression system. Jintropin has the same amino acid sequence with 191 residues as the native human growth hormone produced in the human body. Jintropin is used to treat GH deficiency and a few other legitimate disorders (see Growth hormone treatment). It also has a number of controversial uses (see HGH controversies).
Jintropin is approved for use in China. It is not approved for sale or import in the United States Since early 2007, GeneScience has stated on its website that it does not ship Jintropin out of China, but the United States accuses the company of supplying human growth hormone smuggled into the U.S.
In September 2007, a U.S. federal grand jury indicted GeneScience and its CEO, Lei Jin, on charges of smuggling. U.S. authorities say that Jin imported illegal growth hormone into the country and marketed the drugs through web sites under the brand name "Jintropin."
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