John Herbert Humphrey CBE FRS FRCP (16 December 1915 – 25 December 1987) was a British bacteriologist and immunologist.
Humphrey was the son of the engineer H. A. Humphrey and his wife Mary Elizabeth (née Horniblow). He was educated at Winchester School, and Trinity College, Cambridge. There he met his wife Janet, the daughter of Nobel Prize–winning physiologist Archibald Hill. They had five children, including Nicholas Humphrey, and brought up Humphrey's nephew and niece after the death of Humphrey's brother.
In November 1956 Humphrey founded the British Society for Immunology alongside Robin Coombs, Bob White, and Avrion Mitchison.
He was elected a Fellow of the Royal Society in 1963. He delivered the 1981 Croonian Lecture to the Royal College of Physicians on The Value of Immunological Concepts in Medicine