|John S. Kanzius|
John S. Kanzius, circa 2005
March 1, 1944|
Washington, Pennsylvania, United States
|Died||February 18, 2009
Fort Myers, Florida, United States
|Cause of death||Pneumonia, Lymphoid leukemia|
|Resting place||Millcreek Township, Erie County, Pennsylvania|
|Residence||Sanibel, Florida, United States|
|Alma mater||Trinity High School (Washington, Pennsylvania)|
|Occupation||Radio and television engineer|
|Known for||RF generator|
|Home town||Erie, Pennsylvania, United States|
John S. Kanzius (March 1, 1944 – February 18, 2009) was an American inventor, radio and TV engineer, one-time station owner and ham radio operator (Call Sign K3TUP) from Erie, Pennsylvania. He invented a method that, he said, could treat virtually all forms of cancer, with no side effects, and without the need for surgery or medication.[needs update] He also demonstrated a device that generated flammable hydrogen-containing gas from salt-water-solution by the use of radiowaves. In the media this was dubbed "burning salt water". Both effects involve the use of his radio frequency transmitter.
Kanzius, an autodidact, stated that he was motivated to research the subject of cancer treatment by his own experiences undergoing chemotherapy for treatment of non-Hodgkin's lymphoma. He died of B-cell leukemia with complications from pneumonia without seeing FDA approval and commercialization of his invention.
Kanzius RF Therapy is an experimental cancer treatment that employs a combination of either gold or carbon nanoparticles and radio waves to heat and destroy cancer cells without damaging healthy cells.
The specific absorption rate for radio waves by living tissue in the proposed wavelengths and intensity levels is very low. Metals absorb this energy much more efficiently than tissue through dielectric heating; Richard Smalley has suggested that carbon nanotubes could be used to similar purpose. If nanoparticles were to be preferentially bound to cancer sites, cancer cells could be destroyed or induced into apoptosis while leaving healthy tissue relatively unharmed. This preferential targeting represents a major technical challenge. According to a presentation by Dr. Steven Curley, the types of cancer potentially treatable using Kanzius RF therapy include essentially all forms of cancer.
Kanzius built a prototype Kanzius RF device in his home, and formed Therm Med, LLC to test and market his inventions. The device was successfully tested at University of Pittsburgh Medical Center in 2005. As of 2007-04-23, preliminary research using the device at The University of Texas M. D. Anderson Cancer Center and the University of Pittsburgh Medical Center has shown early promise. If federal approval is granted, testing on human patients may follow. An article published in late 2010 illustrates that radiofrequency fields induce intracellular hyperthermia and necrosis in pancreatic tumors without injury to the human pancreatic tissue grafts tested.
Later in 2007, Kanzius claimed that the same radio frequency transmitter can also be used to generate a hydrogen-oxygen mixture dissociated from salt water. In a column in the journal Nature, it was pointed out that since water is the left over product from burning Hydrogen, it can not be used as a fuel by generating hydrogen and then burning it without an equal or greater amount of input energy than output since it would violate the laws of thermodynamics. The discovery was made accidentally while he was researching the use of radio waves for desalination. Kanzius said that "In this case we weren't looking for energy, we were looking for something that might do desalinization. The more we tried desalinization, the more heat we produced, until we got fire". Kanzius admitted that this process could not be considered an energy source, as more energy is used to produce the RF signal than can be obtained from the burning gas and stated in July 2007 that he never claimed his discovery would replace oil, asserting only that his discovery was "thought provoking".
According to Rustum Roy, a materials scientist at Pennsylvania State University, "The salt water isn't burning per se, despite appearances. The radio frequencies act to weaken the bonds between the elements that make up salt water, releasing the hydrogen. Once ignited, the hydrogen will burn as long as it is exposed to the frequencies". The temperature and flame color varies with water solutions and concentrations.
- Tanya Simon (.February 11, 2009). "The Kanzius Machine: A Cancer Cure?". CBSNews.com.
- Christopher J. Gannon; Paul Cherukuri, Boris I. Yakobson, Laurent Cognet, John S. Kanzius, Carter Kittrell, R. Bruce Weisman, Matteo Pasquali, Howard K. Schmidt, Richard E. Smalley, Steven A. Curley (October 24, 2007). "Carbon nanotube-enhanced thermal destruction of cancer cells in a noninvasive radiofrequency field". Cancer (Wiley) 110 (12): 2654–65. doi:10.1002/cncr.23155. PMID 17960610. "Our results demonstrate that SWNTs can be used as a therapeutic agent to treat malignant tumors through RF-induced thermoablation, not just as a vector for the delivery of anticancer agents."
- Klune, J.R.; Jeyabalan, G., Chory, E.S., Kanzius, J., Geller, D.A. (February 2007). "Pilot investigation of a new instrument for non-invasive radiofrequency ablation of cancer". Journal of Surgical Research 137 (2): 263. doi:10.1016/j.jss.2006.12.293. Retrieved 2007-09-17. "Exposure to the radiowave ﬁeld produced in vitro cell death as well as in vivo tissue destruction when metal ion enhancer solutions were utilized. Future work will focus on specific tumor destruction with tagged enhancer solutions and targeting of in vivo tumors."
- Associated Press (2005-05-11). "Center to test radio wave cancer treatment". First Coast News. Retrieved 2007-09-15.
- "Cancer patient invents treatment machine". CBS13. August 27, 2007. Archived from the original on 2007-08-31. Retrieved 2007-09-10.
- Paul Cherukuri; Christopher J. Gannon, Tonya K. Leeuw, Howard K. Schmidt, Richard E. Smalley, Steven A. Curley and R. Bruce Weisman (2006-12-12). "Mammalian pharmacokinetics of carbon nanotubes using intrinsic near-infrared fluorescence" (PDF). Proceedings of the National Academy of Sciences of the United States of America 103 (50): 18882–86. Bibcode:2006PNAS..10318882C. doi:10.1073/pnas.0609265103. PMC 1665645. PMID 17135351.
- C. J. Gannon, P. Mukherjee and S. A. Curley. "In vitro gold nanoparticle targeting enhances non-invasive radiofrequency destruction of human gastrointestinal malignancies". Poster presented at the 2007 Gastrointestinal Cancers Symposium by Dr. Christopher J. Gannon, M.D.
- Peter Panepento (2007). "Cancer Therapy Takes Next Step". Erie Times-News. Archived from the original on 2007-11-21. Retrieved 2007-10-31.
- "'Hurst hosts Kanzius cancer symposium". Mercyhurst College. 2007-04-23. Archived from the original on 2007-11-17. Retrieved 2007-09-16.
- RF-Induced Thermal Destruction of Cancer Cells Presentation by Steven Curley, accessed November 2, 2007[dead link]
- "Cancer survivor John Kanzius isn't a doctor". Fox News. 2007-05-11. Retrieved 2007-09-16.
- David Templeton (2005-02-20). "UPMC set to test cancer treatment". Pittsburgh Post-Gazette. Retrieved 2007-10-31.
- "Bio for Dr. Steven A. Curley". Alliance for NanoHealth. 2007-02-13. Archived from the original on 2008-02-23. Retrieved 2007-09-16.
- O'Mara, Michael (2007-09-12). "Salt water fuel gets major university review". WKYC. Retrieved 2007-09-14. Note: This video transcript, although published in September 2007, contains quotes by Kanzius from May, as the video contained archive footage. For more information, please see the discussion on this issue.
- David Templeton (2007-05-02). "Cancer research inspires Erie community". Pittsburgh Post-Gazette. Retrieved 2007-09-17. "Dr. Curley has submitted two research manuscripts for publication and was unable to provide the latest results. But he said he is testing the treatment of human cancer strains in animals. (...) "This is the most exciting new therapy for cancer that I have seen in over 20 years of cancer research," he said."
- "Noninvasive Radiofrequency Field Destruction of Pancreatic Adenocarcinoma Xenografts Treated with Targeted Gold Nanoparticles". Clinical Cancer Research.
- O'Mara, Michael (September 12, 2007). Burning Water. Erie, P.A.: WKYC. Retrieved 2007-09-14. Note: This broadcast video, although aired in September 2007, contains archive footage of John Kanzius from May 2007. For more information, please see the discussion on this issue.
- Ball, Philip. "Burning water and other myths". news@nature. doi:10.1038/news070910-13.
- Ogden, Shannon (2007-07-05). "Salt Water Fuel". First Coast News. Retrieved 2007-07-26.
- Templeton, David (2007-09-09). "Salt water as fuel? Erie man hopes so". Pittsburgh Post-Gazette. Retrieved 2007-09-10.
- John Kanzius Cancer Research Official Web Site
- The Kanzius Project published by the Erie Times-News
- Florida Man Invents Machine To Turn Water Into Fire wpbf-TV
- Templeton, David (2007-09-09). "Salt water as fuel? Erie man hopes so". Pittsburgh Post-Gazette. Retrieved 2009-04-08.
- "Sending his cancer a signal" Los Angeles Times article (November 2, 2007)
- "The Kanzius Machine: A Cancer Cure?" 60 Minutes story
- Nature News disproves water as fuel Nature (journal) News article