Prior to the 2012 season, Schoop was ranked by Baseball America as the Orioles third best prospect and the 82nd best overall.
Schoop was recalled by the Orioles from the Triple-A Norfolk Tides on September 3, 2013.
In his first major league at-bat on September 25, 2013, Schoop hit a single off Toronto Blue Jays pitcher Esmil Rogers. Two at-bats later, he hit his first career home run off Kyle Drabek, with a distance measured at 430 feet. He finished the game 2-for-3 with a home run, an RBI, a walk, and 3 runs scored.