Ortiz made his professional debut for San Lorenzo in 2004. He was loaned to Arsenal de Sarandí for the 2006–07 season so he played no part in San Lorenzo's Clausura winning campaign. He returned to San Lorenzo for the start of the 2007 Apertura.
In 2007 he moved to Swedish club AIK. Although he was plagued by injuries during his debut season for the club, he established himself as a key player for the team during the 2009 campaign where they won the Double. In June 2010, AIK and Jorge Ortiz mutually decided to break off their contract, which would have expired in December 2011.