KCNK16

Potassium channel, subfamily K, member 16
Identifiers
Symbols	KCNK16; K2p16.1; MGC133123; TALK-1; TALK1
External IDs	OMIM: 607369 MGI: 1921821 HomoloGene: 75328 IUPHAR: K2P16.1 GeneCards: KCNK16 Gene
Gene Ontology
Molecular function	• voltage-gated ion channel activity; • potassium channel activity;
Cellular component	• membrane; • integral to membrane;
Biological process	• ion transport; • potassium ion transport; • potassium ion transmembrane transport;
	Sources: Amigo / QuickGO
Orthologs

From Wikipedia, the free encyclopedia

Jump to: navigation, search

Potassium channel subfamily K member 16 is a protein that in humans is encoded by the KCNK16 gene.^[1]^[2] The protein encoded by this gene, K_2P16.1, is a potassium channel containing two pore-forming P domains.^[1]^[2]

[edit] See also

Tandem pore domain potassium channel

[edit] References

^ ^a ^b Girard C, Duprat F, Terrenoire C, Tinel N, Fosset M, Romey G, Lazdunski M, Lesage F (Mar 2001). "Genomic and functional characteristics of novel human pancreatic 2P domain K(+) channels". Biochem Biophys Res Commun 282 (1): 249–56. doi:10.1006/bbrc.2001.4562. PMID 11263999.
^ ^a ^b Goldstein SA, Bayliss DA, Kim D, Lesage F, Plant LD, Rajan S (Dec 2005). "International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels". Pharmacol Rev 57 (4): 527–40. doi:10.1124/pr.57.4.12. PMID 16382106.

[edit] Further reading

Mungall AJ, Palmer SA, Sims SK et al (2003). "The DNA sequence and analysis of human chromosome 6". Nature 425 (6960): 805–11. doi:10.1038/nature02055. PMID 14574404.
Strausberg RL, Feingold EA, Grouse LH et al (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
Goldstein SA, Bockenhauer D, O'Kelly I, Zilberberg N (2001). "Potassium leak channels and the KCNK family of two-P-domain subunits". Nat. Rev. Neurosci. 2 (3): 175–84. doi:10.1038/35058574. PMID 11256078.
Han J, Kang D, Kim D (2003). "Functional properties of four splice variants of a human pancreatic tandem-pore K+ channel, TALK-1". Am. J. Physiol., Cell Physiol. 285 (3): C529–38. doi:10.1152/ajpcell.00601.2002. PMID 12724142.
Gierten J, Ficker E, Bloehs R et al (2008). "Regulation of two-pore-domain (K2P) potassium leak channels by the tyrosine kinase inhibitor genistein". Br. J. Pharmacol. 154 (8): 1680–90. doi:10.1038/bjp.2008.213. PMC 2518462. PMID 18516069. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2518462.

[edit] External links

MeSH KCNK16+protein,+human

This membrane protein-related article is a stub. You can help Wikipedia by expanding it.

[pmid11263999-0] Girard C, Duprat F, Terrenoire C, Tinel N, Fosset M, Romey G, Lazdunski M, Lesage F (Mar 2001). "Genomic and functional characteristics of novel human pancreatic 2P domain K(+) channels". Biochem Biophys Res Commun 282 (1): 249–56. doi:10.1006/bbrc.2001.4562. PMID 11263999.

[pmid16382106-1] Goldstein SA, Bayliss DA, Kim D, Lesage F, Plant LD, Rajan S (Dec 2005). "International Union of Pharmacology. LV. Nomenclature and molecular relationships of two-P potassium channels". Pharmacol Rev 57 (4): 527–40. doi:10.1124/pr.57.4.12. PMID 16382106.

[1]

[2]

KCNK16

Contents

[edit] See also

[edit] References

[edit] Further reading

[edit] External links

Personal tools

Namespaces

Variants

Views

Actions

Search

Navigation

Interaction

Toolbox

Print/export