KCTD13

Potassium channel tetramerisation domain containing 13
Identifiers
Symbols	KCTD13; PDIP1; POLDIP1; hBACURD1
External IDs	OMIM: 608947 MGI: 1923739 HomoloGene: 27800 GeneCards: KCTD13 Gene
Gene Ontology Molecular function • ubiquitin-protein ligase activity • voltage-gated potassium channel activity • GTP-Rho binding • identical protein binding Cellular component • nucleus • voltage-gated potassium channel complex • membrane • Cul3-RING ubiquitin ligase complex Biological process • DNA replication • potassium ion transport • cell migration • protein ubiquitination • negative regulation of Rho protein signal transduction • stress fiber assembly • proteasomal ubiquitin-dependent protein catabolic process Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	253980	233877
Ensembl	ENSG00000174943	ENSMUSG00000030685
UniProt	Q8WZ19	Q8BGV7
RefSeq (mRNA)	NM_178863.2	NM_172747.2
RefSeq (protein)	NP_849194.1	NP_766335.1
Location (UCSC)	Chr 16: 29.92 – 29.94 Mb	Chr 7: 134.07 – 134.09 Mb
PubMed search	[1]	[2]

BTB/POZ domain-containing protein KCTD13 is a protein that in humans is encoded by the KCTD13 gene.

Interactions

KCTD13 has been shown to interact with PCNA.

Further reading

• Kutsenko AS, Gizatullin RZ, Al-Amin AN, et al. (2002). "NotI flanking sequences: a tool for gene discovery and verification of the human genome". Nucleic Acids Res. 30 (14): 3163–70. doi:10.1093/nar/gkf428. PMC 135748. PMID 12136098. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=135748. 
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241. 
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928. 
• Wan D, Gong Y, Qin W, et al. (2004). "Large-scale cDNA transfection screening for genes related to cancer development and progression". Proc. Natl. Acad. Sci. U.S.A. 101 (44): 15724–9. doi:10.1073/pnas.0404089101. PMC 524842. PMID 15498874. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=524842. 
• Zhou J, Hu X, Xiong X, et al. (2005). "Cloning of two rat PDIP1 related genes and their interactions with proliferating cell nuclear antigen". J. Exp. Zoolog. Part a Comp. Exp. Biol. 303 (3): 227–40. doi:10.1002/jez.a.150. PMID 15726626. 
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 
• Tomaru T, Satoh T, Yoshino S, et al. (2006). "Isolation and characterization of a transcriptional cofactor and its novel isoform that bind the deoxyribonucleic acid-binding domain of peroxisome proliferator-activated receptor-gamma". Endocrinology 147 (1): 377–88. doi:10.1210/en.2005-0450. PMID 16239304.