KHOT signed on the air in July 1996 carrying a country music format known as "Young Buck Country". Before the station was on the air, the call letters were KXLL. The call letters were changed shortly after sign on to KBUQ to complement the "Young Buck Country" branding.
On October, 10 1997, the format changed to Urban Adult Contemporary with a call letter change to complement the new branding, "Hot 105.9". The format later moved to a Rhythmic Oldies direction. The station then changed call letters to KHOT, which moved from 100.3 in 1997. At that time the station was owned by New Century Arizona Broadcasting.
Hot 105.9 dropped most of its current R&B hits to focus more on a Rhythmic Oldies direction playing mostly 1970s and 1980s R&B and Disco, which most Jammin Oldies stations at that time were doing. In 1999, KHOT was sold to Hispanic Broadcasting Corporation and flipped to its current format. The 105.3 frequency was added in 2001 creating a simulcast.
KHOT's signature program is Piolín Por La Mañana ("Tweety in the Morning"), hosted by Eddie "Piolín" Sotelo. The program originates from Los Angeles-based sister station KSCA, and is a popular show among Spanish-speaking Hispanics in Phoenix.
The PM drive show is known as El Show Del Gatillero Del La Tarde.