KIF1B

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Kinesin family member 1B
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols KIF1B ; CMT2; CMT2A; CMT2A1; HMSNII; KLP; NBLST1
External IDs OMIM605995 MGI108426 HomoloGene99835 ChEMBL: 5889 GeneCards: KIF1B Gene
Orthologs
Species Human Mouse
Entrez 23095 16561
Ensembl ENSG00000054523 ENSMUSG00000063077
UniProt O60333 Q60575
RefSeq (mRNA) NM_015074 NM_001290995
RefSeq (protein) NP_055889 NP_001277924
Location (UCSC) Chr 1:
10.27 – 10.44 Mb
Chr 4:
149.18 – 149.31 Mb
PubMed search [1] [2]

Kinesin-like protein KIF1B is a protein that in humans is encoded by the KIF1B gene.[1][2][3]


Clinical significance[edit]

It is associated with Charcot–Marie–Tooth disease 2A.

Interactions[edit]

KIF1B has been shown to interact with GIPC1.[4]

References[edit]

  1. ^ Zhao C, Takita J, Tanaka Y, Setou M, Nakagawa T, Takeda S, Yang HW, Terada S, Nakata T, Takei Y, Saito M, Tsuji S, Hayashi Y, Hirokawa N (Jun 2001). "Charcot-Marie-Tooth disease type 2A caused by mutation in a microtubule motor KIF1Bbeta". Cell 105 (5): 587–97. doi:10.1016/S0092-8674(01)00363-4. PMID 11389829. 
  2. ^ Nagai M, Ichimiya S, Ozaki T, Seki N, Mihara M, Furuta S, Ohira M, Tomioka N, Nomura N, Sakiyama S, Kubo O, Takakura K, Hori T, Nakagawara A (May 2000). "Identification of the full-length KIAA0591 gene encoding a novel kinesin-related protein which is mapped to the neuroblastoma suppressor gene locus at 1p36.2". Int J Oncol 16 (5): 907–16. doi:10.3892/ijo.16.5.907. PMID 10762626. 
  3. ^ "Entrez Gene: KIF1B kinesin family member 1B". 
  4. ^ Bunn, R C; Jensen M A; Reed B C (Apr 1999). "Protein Interactions with the Glucose Transporter Binding Protein GLUT1CBP That Provide a Link between GLUT1 and the Cytoskeleton". Mol. Biol. Cell 10 (4): 819–32. doi:10.1091/mbc.10.4.819. ISSN 1059-1524. PMC 25204. PMID 10198040. 

Further reading[edit]

External links[edit]