KIF4A

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Kinesin family member 4A
Identifiers
Symbols KIF4A ; KIF4; KIF4G1
External IDs OMIM300521 MGI108389 HomoloGene69022 ChEMBL: 6163 GeneCards: KIF4A Gene
RNA expression pattern
PBB GE KIF4A 218355 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 24137 16571
Ensembl ENSG00000090889 ENSMUSG00000034311
UniProt O95239 P33174
RefSeq (mRNA) NM_012310 NM_008446
RefSeq (protein) NP_036442 NP_032472
Location (UCSC) Chr X:
69.51 – 69.64 Mb
Chr X:
100.63 – 100.73 Mb
PubMed search [1] [2]

Chromosome-associated kinesin KIF4A is a protein that in humans is encoded by the KIF4A gene.[1][2]

Kinesins, such as KIF4A, are microtubule-based motor proteins that generate directional movement along microtubules. They are involved in many crucial cellular processes, including cell division (Zhu and Jiang, 2005).[supplied by OMIM][2]

Interactions[edit]

KIF4A has been shown to interact with HMG20B[3] and DNMT3B.[4]

References[edit]

  1. ^ Ha MJ, Yoon J, Moon E, Lee YM, Kim HJ, Kim W (Jun 2000). "Assignment of the kinesin family member 4 genes (KIF4A and KIF4B) to human chromosome bands Xq13.1 and 5q33.1 by in situ hybridization". Cytogenet Cell Genet 88 (1–2): 41–2. doi:10.1159/000015482. PMID 10773663. 
  2. ^ a b "Entrez Gene: KIF4A kinesin family member 4A". 
  3. ^ Lee, Young Mi; Kim Wankee (Sep 2003). "Association of human kinesin superfamily protein member 4 with BRCA2-associated factor 35". Biochem. J. (England) 374 (Pt 2): 497–503. doi:10.1042/BJ20030452. PMC 1223617. PMID 12809554. 
  4. ^ Geiman, Theresa M; Sankpal Umesh T, Robertson Andrea K, Chen Yue, Mazumdar Manjari, Heale Jason T, Schmiesing John A, Kim Wankee, Yokomori Kyoko, Zhao Yingming, Robertson Keith D (2004). "Isolation and characterization of a novel DNA methyltransferase complex linking DNMT3B with components of the mitotic chromosome condensation machinery". Nucleic Acids Res. (England) 32 (9): 2716–29. doi:10.1093/nar/gkh589. PMC 419596. PMID 15148359. 

Further reading[edit]