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Kinesin light chain 2
Protein KLC2 PDB 3CEQ.png
Rendering based on PDB 3CEQ.
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols KLC2 ; FLJ12387
External IDs OMIM611729 MGI107953 HomoloGene22468 GeneCards: KLC2 Gene
RNA expression pattern
PBB GE KLC2 218906 x at tn.png
More reference expression data
Species Human Mouse
Entrez 64837 16594
Ensembl ENSG00000174996 ENSMUSG00000024862
UniProt Q9H0B6 Q91YS4
RefSeq (mRNA) NM_001134774 NM_008451
RefSeq (protein) NP_001128246 NP_032477
Location (UCSC) Chr 11:
66.02 – 66.04 Mb
Chr 19:
5.11 – 5.12 Mb
PubMed search [1] [2]

Kinesin light chain 2 is a protein that in humans is encoded by the KLC2 gene.[1][2]


KLC2 has been shown to interact with MAPK8IP3[3] and KIF5B.[1][4]


  1. ^ a b Rahman A, Friedman DS, Goldstein LS (July 1998). "Two kinesin light chain genes in mice. Identification and characterization of the encoded proteins". J Biol Chem 273 (25): 15395–403. doi:10.1074/jbc.273.25.15395. PMID 9624122. 
  2. ^ "Entrez Gene: KLC2 kinesin light chain 2". 
  3. ^ Bowman, A B; Kamal A; Ritchings B W; Philp A V; McGrail M; Gindhart J G; Goldstein L S (November 2000). "Kinesin-dependent axonal transport is mediated by the sunday driver (SYD) protein". Cell (UNITED STATES) 103 (4): 583–94. doi:10.1016/S0092-8674(00)00162-8. ISSN 0092-8674. PMID 11106729. 
  4. ^ Rahman, A; Kamal A; Roberts E A; Goldstein L S (September 1999). "Defective Kinesin Heavy Chain Behavior in Mouse Kinesin Light Chain Mutants". J. Cell Biol. (UNITED STATES) 146 (6): 1277–88. doi:10.1083/jcb.146.6.1277. ISSN 0021-9525. PMC 2156125. PMID 10491391. 

Further reading[edit]