KML-010

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KML-010
KML-010 structure.png
Systematic (IUPAC) name
8-[4-(4-fluorophenyl)-4-oxobutyl]-1-methyl-1,3,8-triazaspiro[4.5]decan-4-one
Clinical data
Legal status ?
Identifiers
ATC code ?
PubChem CID 10404584
ChemSpider 8580022 YesY
Chemical data
Formula C18H24FN3O2 
Mol. mass 333.400 g/mol
 YesY (what is this?)  (verify)

KML-010 is a drug derived from spiperone. It functions as a highly selective 5-HT2A receptor antagonist, with negligible affinity for the 5-HT1A or 5-HT2C receptors, and over 400-fold lower affinity for the D2 receptor in comparison to spiperone.[1]

See also[edit]

References[edit]

  1. ^ Glennon RA, Metwally K, Dukat M, Ismaiel AM, De los Angeles J, Herndon J, Teitler M, Khorana N (June 2002). "Ketanserin and spiperone as templates for novel serotonin 5-HT(2A) antagonists". Current Topics in Medicinal Chemistry 2 (6): 539–58. doi:10.2174/1568026023393787. PMID 12052193.