KRT23

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Keratin 23 (histone deacetylase inducible)
Identifiers
Symbols KRT23 ; CK23; HAIK1; K23
External IDs OMIM606194 MGI2148866 HomoloGene9172 GeneCards: KRT23 Gene
RNA expression pattern
PBB GE KRT23 218963 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 25984 94179
Ensembl ENSG00000108244 ENSMUSG00000006777
UniProt Q9C075 Q99PS0
RefSeq (mRNA) NM_001282433 NM_033373
RefSeq (protein) NP_001269362 NP_203537
Location (UCSC) Chr 17:
39.08 – 39.09 Mb
Chr 11:
99.48 – 99.49 Mb
PubMed search [1] [2]

Keratin, type I cytoskeletal 23 is a protein that in humans is encoded by the KRT23 gene.[1][2][3]

The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21.[3]

References[edit]

  1. ^ Zhang JS, Wang L, Huang H, Nelson M, Smith DI (Jan 2001). "Keratin 23 (K23), a novel acidic keratin, is highly induced by histone deacetylase inhibitors during differentiation of pancreatic cancer cells". Genes Chromosomes Cancer 30 (2): 123–35. doi:10.1002/1098-2264(2000)9999:9999<::AID-GCC1070>3.0.CO;2-W. PMID 11135429. 
  2. ^ Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW (Jul 2006). "New consensus nomenclature for mammalian keratins". J Cell Biol 174 (2): 169–74. doi:10.1083/jcb.200603161. PMC 2064177. PMID 16831889. 
  3. ^ a b "Entrez Gene: KRT23 keratin 23 (histone deacetylase inducible)". 

Further reading[edit]