KRT32

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Keratin 32
Identifiers
Symbols KRT32 ; HA2; HKA2; KRTHA2; hHa2
External IDs OMIM602760 MGI1309995 HomoloGene68246 GeneCards: KRT32 Gene
RNA expression pattern
PBB GE KRT32 207146 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 3882 16670
Ensembl ENSG00000108759 ENSMUSG00000046095
UniProt Q14532 Q62168
RefSeq (mRNA) NM_002278 NM_001159374
RefSeq (protein) NP_002269 NP_001152846
Location (UCSC) Chr 17:
39.62 – 39.62 Mb
Chr 11:
100.08 – 100.09 Mb
PubMed search [1] [2]

Keratin, type I cuticular Ha2 is a protein that in humans is encoded by the KRT32 gene.[1][2][3][4]

The protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription.[4]

References[edit]

  1. ^ Rogers MA, Nischt R, Korge B, Krieg T, Fink TM, Lichter P, Winter H, Schweizer J (Nov 1995). "Sequence data and chromosomal localization of human type I and type II hair keratin genes". Exp Cell Res 220 (2): 357–62. doi:10.1006/excr.1995.1326. PMID 7556444. 
  2. ^ Rogers MA, Winter H, Langbein L, Krieg T, Schweizer J (Dec 1996). "Genomic characterization of the human type I cuticular hair keratin hHa2 and identification of an adjacent novel type I hair keratin gene hHa5". J Invest Dermatol 107 (4): 633–8. doi:10.1111/1523-1747.ep12584243. PMID 8823373. 
  3. ^ Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW (Jul 2006). "New consensus nomenclature for mammalian keratins". J Cell Biol 174 (2): 169–74. doi:10.1083/jcb.200603161. PMC 2064177. PMID 16831889. 
  4. ^ a b "Entrez Gene: KRT32 keratin 32". 

Further reading[edit]