The first call sign of the station was KELR. The radio equipment was installed in 1962. The call sign was changed to KCAN beginning on 3 November 1978. On 18 July 1985, the station changed its call sign to the current KZUE.
KZUE stood for "The Zoo". In the past, 102.7 had the call sign KZUE. In the spirit of the old KZUE on 102.7, the initial format as KZUE was a form of popular rock and roll. The format did not last long. The station was then sold to Nancy Galvan who changed the station to become the first Spanish-language station in the Metropolitan Oklahoma City area.
1460 was the second station standard-band (AM) to be licensed to El Reno. KCHE, which was started in 1948 on 1500 and moved to 1590 in 1949, ceased operations by 1951. KCHE was not affiliated in any way with the present 1460 radio station.