Kai-Uwe von Hassel (21 April 1913 – 8 May 1997) was a German politician from Schleswig-Holstein associated with the CDU party.
Von Hassel was born in Gare, German East Africa (now in Lushoto, Tanga Region, Tanzania).
In 1954-1963 he was Minister-President of Schleswig-Holstein. From 1955-1956, he was President of the German Bundesrat. He was closely associated with Ludwig Erhard's two Chancellorships, serving as Minister of Defense from 16 October 1963 to 1 December 1966. He then served in Kurt Georg Kiesinger's Chancellorship from 1 December 1966 to 21 October 1969 as "Minister of Displaced Persons, Refugees, and War Victims". His son and naval aviator Oberleutnant zur See Joachim von Hassel was killed in a Lockheed F-104 Starfighter crash on 10 March 1970.
Following this ministership, he became president of the Bundestag from 5 February 1969 to 13 December 1972, after the previous president (Eugen Gerstenmaier) resigned amidst a financial scandal. He died aged 84 during the Charlemagne Award ceremony in the Aachen city hall in 1997.