Tso began her career as a general news reporter for the AAP after graduating with a commerce degree from Griffith University in Queensland. She also studied for a Masters In Journalism at both the University of Westminster in London and the University of Technology, Sydney before joining the ABC in 2002. In 2005 She joined Nine Network as a finance reporter before presenting the evening edition of Sky Business Report on Sky News Australia from 2006 - 2007.
In October 2008 Karen left Nine News for CNBC Asia where she anchored Squawk Australia a concise one-hour show with the mission of delivering Australian business news to the world, and global business to Australia.
In early 2010, as part of a programming revamp, Karen Tso moved to Singapore to take up a new role as co-anchor of Asia Squawk Box, along with veteran anchor Martin Soong and Bernard Lo. Tso also began co-anchoring a new one-hour morning show with Bernard Lo titled "The Call".
- "Biography of Karen Tso". Retrieved 2010-04-25. Profile of Karen Tso - Anchor of Squawk Australia.
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