|• Total||2,127.25 km2 (821.34 sq mi)|
|Highest elevation||2,460 m (8,070 ft)|
|Lowest elevation||200 m (700 ft)|
|Population (2010 Census)|
|• Density||160/km2 (430/sq mi)|
|Time zone||WIB (UTC+7)|
Karo Regency is a regency of North Sumatra, Indonesia. It is situated in the Bukit Barisan mountains. The regency covers an area of 2,127.25 square kilometres and according to the 2010 census it had a population of 350,479. 60.99% of the regency is forested. Its regency seat is Kabanjahe. The Batak Karo language is spoken in the regency, as well as Indonesian language. It borders Southeast Aceh Regency in Aceh Province to the west, Deli Serdang Regency and Langkat Regency to the north, Dairi Regency and Toba Samosir Regency to the south, and Deli Serdang Regency and Simalungun Regency to the east.
The GDP per capita of Karo Regency in 2005 was 11.65 million rupiah, approximately US$1,200. 74% of the population work in agriculture, which comprises 60% of regional GDP.  The second-largest sector is government, which comprises 11% of the regional GDP.
The regency is divided administratively into 17 districts (kecamatan):
- Seta,William J. Atlas Lengkap Indonesia dan Dunia (untuk SD, SMP, SMU, dan Umum). Pustaka Widyatama. p. 9. ISBN 979-610-232-3.
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