Karyolysis

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Morphological characteristics of karyolysis and other forms of nuclear destruction.

Karyolysis (Greek karyon = kernel, seed or nucleus, and lýsis from lýein, to separate) is the complete dissolution of the chromatin of a dying cell due to the enzymatic degradation by endonucleases. The whole cell will eventually stain uniformly with eosin after karyolysis. It is usually preceded by karyorrhexis and occurs mainly as a result of necrosis, while in apoptosis after karyorrhexis the nucleus usually dissolves into apoptotic bodies.[1]

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  1. ^ Cotran; Kumar, Collins (1998). Robbins Pathologic Basis of Disease. Philadelphia: W.B Saunders Company. ISBN 0-7216-7335-X.