Kazusa-Ichinomiya Station was opened on April 17, 1898 as Ichinomiya Station(一ノ宮駅,Ichinomiya-eki?) on the Bōsō Railway. The line was further extended to Chiba by December 13, 1899. On September 1, 1907, the Bōsō Railway was nationalized and became part of the Japanese Government Railways, which was transformed into the Japan National Railways (JNR) after World War II. The station name was changed to the present name on January 1, 1917. Freight operations were discontinued on July 1, 1971. The station was absorbed into the JR East network upon the privatization of the Japan National Railways on April 1, 1987.