|Jmol-3D images||Image 1|
|Molar mass||434.50 g mol−1|
| (what is: / ?)
Except where noted otherwise, data are given for materials in their standard state (at 25 °C or 77 °F, 100 kPa)
Triamcinolone acetonide is a synthetic corticosteroid used to treat various skin conditions, relieve the discomfort of mouth sores and in nasal spray form, to treat allergic rhinitis. It is a more potent derivative of triamcinolone, and is about 8 times as potent as prednisone.
It is also known under the brand names Kenalog and Volon A as an injection to treat allergies, arthritis, eye diseases, intestinal problems and skin diseases.
Triamcinolone acetonide should not be used by those with tuberculosis or untreated fungal, bacterial, systemic viral or herpes simplex infections without consulting a doctor first. Few serious adverse effects were noted in clinical trials, with intranasal formulations and include pharyngitis, rhinitis, headache and epistaxis being the more common ones. Overdosage is unlikely. Uncommonly, systemic effects associated with corticosteroids can occur when large doses of a triamcinolone acetonide preparation are administered and or if it is taken for a long time. As an intravitreal injection, triamcinolone has been used in various eye diseases and has been found useful in reducing macular Edema. Drug trials have found it to be as efficient as anti-VEGF drugs in eyes with artificial lens over a 2-year period. Complications of its use in eye are - cataract and glaucoma. Triamcinolone acetonide as an intraarticular injectable has been used as treatment for a variety of musculoskeletal conditions
When applied as a topical ointment @ USP,0.1% it is used for blistering from poison ivy, oak, and sumac. Applied to skin avoiding eyes, mouth, and genital area. Provides immediate relief and is used before going to oral prednisone.
Uncommonly Intramuscular injection of triamcinolone acetonide may be indicated for the control of severe or incapacitating allergic states for which conventional treatments have failed, such as asthma, atopic dermatitis, contact dermatitis, perennial or seasonal allergic rhinitis, serum sickness, and transfusion and drug hypersensitivity reactions.
Common side effects of traimcinolone acetonide include sore throat, nosebleeds, increased coughing, headache, and runny nose, if these side effects occur consult your doctor when possible.
Rarer, more serious side effects include opportunistic infections (due to suppression of immune responses) and anaphylaxis, if these life threatening side effects occur call 911 or go to the nearest emergency room immediately. Do not attempt to drive while you are suffering from these side effects, have someone else drive you to the nearest hospital or request an ambulance from 911.
Use triamcinolone acetonide exactly as prescribed, overuse of triamcinolone acetonide significantly increases the risk of side effects. Do not use it more often than instructed, in larger doses than instructed, or for a longer time than instructed. Drink water frequently during your regimen, dehydration also increases the risk of side effects occurring.
As with all imunosuppresant drugs, do not begin taking triamcinolone acetonide if you are currently (or have recently been) sick. Avoid contact with sick persons during your entire course of treatment. While using triamcinolone acetonide even minor illnesses (ex. common cold) can be very serious, and may sometimes become life threatening. If you get sick during your regimen, contact your doctor as soon as possible to discuss the risks and benefits of discontinuing the prescription. Do not stop taking triamcinolone acetonide without first consulting your doctor.
Do not take triamcinolone acetonide if you are taking any other steroid or immunosuppresant, or if you have recently undergone any medical procedures involving the administration of steroids (ex. nerve block).
Tell your doctor about all other medications you are taking before using trimcinolone acetonide, many drugs have been demonstrated to increase its concentration in the blood to well above the intended level.
Triamcinolone acetonide is also used in veterinary medicine as an ingredient in topical ointments, also in topical sprays for control of pruritus in dogs. A series of injections with triamcinolone acetonide or another corticosteroid may reduce keloid size and irritation. It is also used as a pre-inductor and/or inductor of birth in cows.