Kenan İmirzalıoğlu was born as the youngest of three children to Mustafa and Yıldız İmirzalıoğlu in the village of Üçem in Balâ, Ankara Province. At age 12, he moved to the city of Ankara for his middle studies. He graduated in Mathematics from Yıldız Technical University.
He caught the eye of director Osman Sınav who cast him in the TV series Deli Yürek (Crazy Heart). He also starred in its spinoff film Deli Yürek: Bumerang Cehennemi (Crazy Heart: Boomerang Hell). He then acted in Alacakaranlık (Dusk) written and directed by Uğur Yücel and Yazı Tura (Toss up) which featured the same cast. In 2005, İmirzalıoğlu played the lead role in Osman Sınav's Aci Hayat (Bitter Life) based on the 1962 film of the same name. He followed that by lead roles in the action films Son Osmanlı Yandım Ali (The Last Ottoman: Knockout Ali) and Kabadayı (For Love and Honor). He returned to television in 2009 with the series Ezel and also starred in the action film Ejder Kapanı (Dragon Trap) directed by Uğur Yücel.