Keratocystic odontogenic tumour
|Keratocystic odontogenic tumour|
|Classification and external resources|
|ICD-10||D16.4 (Maxilla); D16.5 (mandible)|
A keratocystic odontogenic tumour (also keratocystic odontogenic tumor), abbreviated KCOT, is a rare and benign but locally aggressive developmental cystic neoplasm. It most often affects the posterior mandible.
KCOTs are thought to arise from the dental lamina and associated with impacted teeth. Multiple odontogenic keratocysts are a feature of nevoid basal cell carcinoma syndrome. Odotogenic Keratocysts are derived from the Remnants of the Dental Lamina.
As the entity is quite rare, opinions among experts about how to treat KCOTs differ.
- Wide (local) surgical excision.
- Marsupialization - the surgical opening of the (KCOT) cavity and a creation of a marsupial-like pouch, so that the cavity is in contact with the outside for an extended period, e.g. three months.
- Curettage (simple excision & scrape-out of cavity).
- Peripheral ostectomy after curettage and/or enucleation.
- Simple excision.
- Carnoy's solution - usually used in conjunction with excision.
- Enucleation and cryotherapy 
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