|Kevin John Karplus|
|Born||30 Nov 1954
|Residence||Santa Cruz, CA|
|Institutions||University of California, Santa Cruz|
|Alma mater||Stanford University|
|Doctoral advisor||Jeff Ullman|
|Doctoral students||Habib Krit, Soren Soe, Christian Barrett, Rachel Karchin, Firas Khatib, Josue Samayoa, George Shackelford, Grant Thiltgen|
|Known for||Karplus-Strong string synthesis, protein structure prediction particularly success in CASP|
Excellence in Teaching Award UCSC Senate, 2004,Herzog Mathematics Competition, 1973 
Kevin Karplus is a professor at University of California, Santa Cruz, currently in the Biomolecular Engineering Department.
He taught VLSI design and computer engineering for several years, helping create the Computer Engineering Department at University of California, Santa Cruz. He made some contributions to VLSI CAD, particularly to logic minimization, where he invented the if-then-else DAG (a generalization of the binary decision diagram) and a canonical form for it, before switching to protein structure prediction and bioinformatics in 1995.
He has participated in CASP (Critical Assessment of Techniques for Protein Structure Prediction) since CASP2 in 1996, and has been invited to present papers at CASP2, 3, 4, 5, 6, 7, and 8.
Karplus has long been a bicycle advocate. In 1994, the League of American Bicyclists gave him the Phyllis W. Harmon Volunteer-of-the-Year Award. In 2001, he was given a Lifetime Achievement Award by Santa Cruz County Regional Transportation Commission for long standing commitment to improving bicycle transportation in Santa Cruz County. He was also one of the founding members of People Power, a bicycle advocacy group in Santa Cruz.