Kexin

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Kex2p
Identifiers
Symbol KEX2
Entrez 855483
UniProt D6W0V5
Other data
EC number 3.4.21.61

Kexin is a prohormone processing protease found in the budding yeast (S. cerevisiae) that shares structural similarities with the bacterial protease subtilisin.[1] It is encoded by the yeast gene KEX2 and usually referred to in the scientific community as Kex2p. The first mammalian homologue of this protein to be identified was furin.

[edit] References

  1. ^ Rockwell NC, Krysan DJ, Komiyama T, Fuller RS (December 2002). "Precursor processing by kex2/furin proteases". Chem. Rev. 102 (12): 4525–48. doi:10.1021/cr010168i. PMID 12475200. 
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