|Elevation||1,160 m (3,810 ft)|
|Population (2002 Estimate)|
|Time zone||EAT (UTC+3)|
Kiryandongo District is bordered by Nwoya District to the north, Oyam District to the northeast, Apac District to the east, and Masindi District to the south and west. Kiryandongo, the location of the district headquarters, lies approximately 225 kilometres (140 mi), by road, northwest of Kampala, Uganda's capital and largest city. The coordinates of the district are:02 00N, 32 18E (Latitude:2.0000; Longitude:32.3000).
Kiryandongo District was established on 1 July 2010. Prior to that, it was part of Masindi District. The district is part of Bunyoro sub-region, which is coterminous with Bunyoro Kingdom. The districts that constitute Bunyoro sub-region include the following:
In 2002, the sub-region was home to an estimated 750,000 inhabitants, according to the national population and household census conducted that year.
The population of Kiryandongo District according to the 2002 national census was about 187,700. The district population in 2011 is not known.