The place where Kruiningen was built, was one of the islands that later formed Zuid-Beveland. The area was diked by monks of the abbeys of Ten Duinen and Ter Doest. Kruiningen was hit hard during the Flood of 1953, 62 people died and the entire village came for six months under the influence of the tides. The Johanneskerk was rebuilt in the 15th and 16th century after a fire in the 14th century. In the church is the tomb of Arnoud van Cruningen (deceased in 1561), a gentleman from the Van Kruiningen family. The octagonal mill De Oude Molen was built in 1801.