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The Kure Line (呉線 Kuresen) is a railway line operated by West Japan Railway Company (JR West) within Hiroshima Prefecture in Japan. It begins at Mihara Station in Mihara and terminates at Kaitaichi Station in Kaita. It is one of the main lines of JR West. The section between Mihara Station to Hiro Station is branded the "Setouchi Sazanami Line" (Seto Inland Sea Ripple Line) as the sightseeing line. The section between Mihara Station and Hiro Station, most trains run from Hiro Station through Mihara Station to Itozaki Station. On the section between Hiro Station and Kaitaich Station, most trains run from Hiro Station through Kaitaichi Station to Hiroshima Station or Iwakuni Station.
- Operator: West Japan Railway Company (Class-1 railroad)
- Official line length: 87.0 km
- Gauge: 1,067 mm (3 ft 6 in)
- Stations: 28 (including Mihara Station and Kaitaichi Station)
- Double track: none (entirely single track)
- Electrified sections: all (1,500 V DC overhead)
- Closure system: Special automatic closure type (track circuit detection)
- Speed limit: 95 km/h (60 mph)
- Operational command: Hiroshima Integrated Command Center
A 115 series train on an Akiji Liner
- Akiji Liner: Runs the section between Hiroshima Station to Kure Station in about 30 minutes.
- Setouchi Marine View: Sightseeing train operated since October 1, 2005
New 2- and 3-car 227 series electric trains are scheduled to be introduced on the Kure Line from around 2015, replacing older 115 series trains.
- Opened the line between Kaitaichi Station to Kure Station including Yano Station, Saka Station, Tennō Station and Yoshiura Station on December 27, 1903.
- Opened temporary station (Hamasaki Station) on July 28, 1904.
- Rent for Sanyo Railway from December 1, 1904.
- Nationalized from December 1, 1906.
- Named "Kure Line" as one of national rail ways on October 12, 1909.
- Opened Koyaura Station and Closed Hamasaki Station on May 1, 1914.
- Opened temporary station (Akihamasaki Station) on July 21, 1926.
- Opened temporary station (Karyugahama Station) on July 7, 1928.
- Extended the line from Kure Station to Hiro Station and opened Akiaga Station and Hiro Station on March 24, 1935.
- Closed Kawaraishi Station on December 1, 1940.
- Renamed Mitsuuchinoumi Station to Yasuura Station on May 1, 1946.
- Renamed Akimitsu Station to Akitsu Station on December 20, 1949.
- Re-opened Kawaraishi Station on August 1, 1958.
- Closed temporary stations (Karyugahama Station and Akihamasaki Station) on August 1, 1967.
- Electrified the rail way on September 15, 1970.
- Stopped cargo services on December 1, 1986.
- Privatized as JR West on April 1, 1987.
- Opened Kure-Portopia Station on March 19, 1992.
- Opened Akinagahama Station on October 1, 1994.
- Opened Karugahama Station and Mizushiri Station and moved Kawaraishi Station on February 7, 1999.
- Opened Shinhiro Station on March 23, 2002.