A member of the Fang ethnic group, Mébiame was born in Libreville. Under French colonial rule, he became an inspector of federal police in 1956 and was posted in Chad from January 6, 1957 to March 1959. A close associate of President Omar Bongo, he was Vice President of Gabon from 1968 to 1975, when the position was abolished; he was then appointed as Prime Minister and served from April 16, 1975 to May 3, 1990. Subsequently he joined the opposition in the early 1990s.
- La politique africaine en 1969 (1970), Ediafric, page 134 (French).
- David E. Gardinier and Douglas A. Yates, Historical Dictionary of Gabon (2006), Third Edition, page 209.
- "Convention républicaine ?", Africa Intelligence, 8 July 1993 (French).
- David E. Gardinier, "Gabon: Limited Reform and Regime Survival", Political Reform in Francophone Africa (1997), ed. Clark and Gardinier, Westview Press, page 156.
- "Nomination d'un nouveau président de la chambre de commerce", Infosplusgabon, November 7, 2008 (French).
- "Gabon: Chambre de Commerce : Joachim Boussamba passe le flambeau à Léon Mébiame", Gabonews, December 4, 2008 (French).
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