L3MBTL2

L(3)mbt-like 2 (Drosophila)
Rendering based on PDB 2W0T.
Available structures PDB 2W0T, 3CEY, 3F70
Identifiers
Symbols	L3MBTL2; H-l(3)mbt-l; L3MBT
External IDs	OMIM: 611865 MGI: 2443584 HomoloGene: 12882 GeneCards: L3MBTL2 Gene
Gene Ontology Molecular function • transcription corepressor activity • zinc ion binding • methylated histone residue binding • histone binding • metal ion binding Cellular component • nucleus • nucleus Biological process • regulation of transcription, DNA-dependent • chromatin modification Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	83746	214669
Ensembl	ENSG00000100395	ENSMUSG00000022394
UniProt	Q969R5	Q3U164
RefSeq (mRNA)	NM_001003689	NM_145993.4
RefSeq (protein)	NP_001003689	NP_666105.2
Location (UCSC)	Chr 22: 41.6 – 41.63 Mb	Chr 15: 81.49 – 81.52 Mb
PubMed search	[1]	[2]

Lethal(3)malignant brain tumor-like 2 protein is a protein that in humans is encoded by the L3MBTL2 gene.

Further reading

• Dunham I, Shimizu N, Roe BA et al (1999). "The DNA sequence of human chromosome 22". Nature 402 (6761): 489–95. doi:10.1038/990031. PMID 10591208. 
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=310948. 
• Wiemann S, Weil B, Wellenreuther R et al (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=311072. 
• Ogawa H, Ishiguro K, Gaubatz S et al (2002). "A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells". Science 296 (5570): 1132–6. doi:10.1126/science.1069861. PMID 12004135. 
• Strausberg RL, Feingold EA, Grouse LH et al (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241. 
• Ota T, Suzuki Y, Nishikawa T et al (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
• Collins JE, Wright CL, Edwards CA et al (2005). "A genome annotation-driven approach to cloning the human ORFeome". Genome Biol. 5 (10): R84. doi:10.1186/gb-2004-5-10-r84. PMC 545604. PMID 15461802. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=545604. 
• Gerhard DS, Wagner L, Feingold EA et al (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928. 
• Wiemann S, Arlt D, Huber W et al (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528930. 
• Rual JF, Venkatesan K, Hao T et al (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 
• Mehrle A, Rosenfelder H, Schupp I et al (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1347501.