LCMT1
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| Leucine carboxyl methyltransferase 1 | |||||||||||
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 Rendering based on PDB 3IEI. |
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| Identifiers | |||||||||||
| Symbols | LCMT1; LCMT; PPMT1 | ||||||||||
| External IDs | OMIM: 610286 MGI: 1353593 HomoloGene: 41123 GeneCards: LCMT1 Gene | ||||||||||
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| RNA expression pattern | |||||||||||
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| Orthologs | |||||||||||
| Species | Human | Mouse | |||||||||
| Entrez | 51451 | 30949 | |||||||||
| Ensembl | ENSG00000205629 | ENSMUSG00000030763 | |||||||||
| UniProt | Q9UIC8 | n/a | |||||||||
| RefSeq (mRNA) | NM_001032391.1 | NM_025304.3 | |||||||||
| RefSeq (protein) | NP_001027563.1 | NP_079580.2 | |||||||||
| Location (UCSC) | Chr 16: 25.12 – 25.19 Mb |
Chr 7: 130.52 – 130.57 Mb |
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| PubMed search | [1] | [2] | |||||||||
Leucine carboxyl methyltransferase 1 is an enzyme that in humans is encoded by the LCMT1 gene.[1][2]
[edit] Interactions
LCMT1 has been shown to interact with FXR2.[3]
[edit] References
- ^ Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=310876.
- ^ "Entrez Gene: LCMT1 leucine carboxyl methyltransferase 1". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51451.
- ^ Rual, Jean-François; Venkatesan Kavitha, Hao Tong, Hirozane-Kishikawa Tomoko, Dricot Amélie, Li Ning, Berriz Gabriel F, Gibbons Francis D, Dreze Matija, Ayivi-Guedehoussou Nono, Klitgord Niels, Simon Christophe, Boxem Mike, Milstein Stuart, Rosenberg Jennifer, Goldberg Debra S, Zhang Lan V, Wong Sharyl L, Franklin Giovanni, Li Siming, Albala Joanna S, Lim Janghoo, Fraughton Carlene, Llamosas Estelle, Cevik Sebiha, Bex Camille, Lamesch Philippe, Sikorski Robert S, Vandenhaute Jean, Zoghbi Huda Y, Smolyar Alex, Bosak Stephanie, Sequerra Reynaldo, Doucette-Stamm Lynn, Cusick Michael E, Hill David E, Roth Frederick P, Vidal Marc (Oct. 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature (England) 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
[edit] Further reading
- Lee JA, Pallas DC (2007). "Leucine carboxyl methyltransferase-1 is necessary for normal progression through mitosis in mammalian cells.". J. Biol. Chem. 282 (42): 30974–84. doi:10.1074/jbc.M704861200. PMID 17724024.
- Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
- De Baere I, Derua R, Janssens V, et al. (2000). "Purification of porcine brain protein phosphatase 2A leucine carboxyl methyltransferase and cloning of the human homologue.". Biochemistry 38 (50): 16539–47. doi:10.1021/bi991646a. PMID 10600115.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
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