LIN7A

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Lin-7 homolog A (C. elegans)
Protein LIN7A PDB 2dkr.png
PDB rendering based on 2dkr.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols LIN7A ; LIN-7A; LIN7; MALS-1; TIP-33; VELI1
External IDs OMIM603380 MGI2135609 HomoloGene20976 GeneCards: LIN7A Gene
RNA expression pattern
PBB GE LIN7A 206440 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 8825 108030
Ensembl ENSG00000111052 ENSMUSG00000019906
UniProt O14910 Q8JZS0
RefSeq (mRNA) NM_004664 NM_001033223
RefSeq (protein) NP_004655 NP_001028395
Location (UCSC) Chr 12:
81.19 – 81.33 Mb
Chr 10:
107.27 – 107.43 Mb
PubMed search [1] [2]

Lin-7 homolog A is a protein that in humans is encoded by the LIN7A gene.[1][2][3]


Interactions[edit]

LIN7A has been shown to interact with KCNJ12,[4][5] DLG1[5] and CASK.[5][6]

References[edit]

  1. ^ Jo K, Derin R, Li M, Bredt DS (Jun 1999). "Characterization of MALS/Velis-1, -2, and -3: a family of mammalian LIN-7 homologs enriched at brain synapses in association with the postsynaptic density-95/NMDA receptor postsynaptic complex". J Neurosci 19 (11): 4189–99. PMID 10341223. 
  2. ^ Bohl J, Brimer N, Lyons C, Vande Pol SB (Mar 2007). "The stardust family protein MPP7 forms a tripartite complex with LIN7 and DLG1 that regulates the stability and localization of DLG1 to cell junctions". J Biol Chem 282 (13): 9392–400. doi:10.1074/jbc.M610002200. PMID 17237226. 
  3. ^ "Entrez Gene: LIN7A lin-7 homolog A (C. elegans)". 
  4. ^ Leonoudakis, Dmitri; Conti Lisa R; Anderson Scott; Radeke Carolyn M; McGuire Leah M M; Adams Marvin E; Froehner Stanley C; Yates John R; Vandenberg Carol A (May 2004). "Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins". J. Biol. Chem. (United States) 279 (21): 22331–46. doi:10.1074/jbc.M400285200. ISSN 0021-9258. PMID 15024025. 
  5. ^ a b c Leonoudakis, Dmitri; Conti Lisa R; Radeke Carolyn M; McGuire Leah M M; Vandenberg Carol A (Apr 2004). "A multiprotein trafficking complex composed of SAP97, CASK, Veli, and Mint1 is associated with inward rectifier Kir2 potassium channels". J. Biol. Chem. (United States) 279 (18): 19051–63. doi:10.1074/jbc.M400284200. ISSN 0021-9258. PMID 14960569. 
  6. ^ Borg, J P; Straight S W, Kaech S M, de Taddéo-Borg M, Kroon D E, Karnak D, Turner R S, Kim S K, Margolis B (Nov 1998). "Identification of an evolutionarily conserved heterotrimeric protein complex involved in protein targeting". J. Biol. Chem. (UNITED STATES) 273 (48): 31633–6. doi:10.1074/jbc.273.48.31633. ISSN 0021-9258. PMID 9822620. 

Further reading[edit]