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Lin-7 homolog A (C. elegans)
Protein LIN7A PDB 2dkr.png
PDB rendering based on 2dkr.
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols LIN7A ; LIN-7A; LIN7; MALS-1; TIP-33; VELI1
External IDs OMIM603380 MGI2135609 HomoloGene20976 GeneCards: LIN7A Gene
RNA expression pattern
PBB GE LIN7A 206440 at tn.png
More reference expression data
Species Human Mouse
Entrez 8825 108030
Ensembl ENSG00000111052 ENSMUSG00000019906
UniProt O14910 Q8JZS0
RefSeq (mRNA) NM_004664 NM_001033223
RefSeq (protein) NP_004655 NP_001028395
Location (UCSC) Chr 12:
81.19 – 81.33 Mb
Chr 10:
107.27 – 107.43 Mb
PubMed search [1] [2]

Lin-7 homolog A is a protein that in humans is encoded by the LIN7A gene.[1][2][3]


LIN7A has been shown to interact with KCNJ12,[4][5] DLG1[5] and CASK.[5][6]


  1. ^ Jo K, Derin R, Li M, Bredt DS (Jun 1999). "Characterization of MALS/Velis-1, -2, and -3: a family of mammalian LIN-7 homologs enriched at brain synapses in association with the postsynaptic density-95/NMDA receptor postsynaptic complex". J Neurosci 19 (11): 4189–99. PMID 10341223. 
  2. ^ Bohl J, Brimer N, Lyons C, Vande Pol SB (Mar 2007). "The stardust family protein MPP7 forms a tripartite complex with LIN7 and DLG1 that regulates the stability and localization of DLG1 to cell junctions". J Biol Chem 282 (13): 9392–400. doi:10.1074/jbc.M610002200. PMID 17237226. 
  3. ^ "Entrez Gene: LIN7A lin-7 homolog A (C. elegans)". 
  4. ^ Leonoudakis, Dmitri; Conti Lisa R; Anderson Scott; Radeke Carolyn M; McGuire Leah M M; Adams Marvin E; Froehner Stanley C; Yates John R; Vandenberg Carol A (May 2004). "Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins". J. Biol. Chem. (United States) 279 (21): 22331–46. doi:10.1074/jbc.M400285200. ISSN 0021-9258. PMID 15024025. 
  5. ^ a b c Leonoudakis, Dmitri; Conti Lisa R; Radeke Carolyn M; McGuire Leah M M; Vandenberg Carol A (Apr 2004). "A multiprotein trafficking complex composed of SAP97, CASK, Veli, and Mint1 is associated with inward rectifier Kir2 potassium channels". J. Biol. Chem. (United States) 279 (18): 19051–63. doi:10.1074/jbc.M400284200. ISSN 0021-9258. PMID 14960569. 
  6. ^ Borg, J P; Straight S W, Kaech S M, de Taddéo-Borg M, Kroon D E, Karnak D, Turner R S, Kim S K, Margolis B (Nov 1998). "Identification of an evolutionarily conserved heterotrimeric protein complex involved in protein targeting". J. Biol. Chem. (UNITED STATES) 273 (48): 31633–6. doi:10.1074/jbc.273.48.31633. ISSN 0021-9258. PMID 9822620. 

Further reading[edit]