LIN7B

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Lin-7 homolog B (C. elegans)
Protein LIN7B PDB 1y74.png
PDB rendering based on 1y74.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols LIN7B ; LIN-7B; MALS-2; MALS2; VELI2
External IDs OMIM612331 MGI1330858 HomoloGene22648 GeneCards: LIN7B Gene
RNA expression pattern
PBB GE LIN7B 219760 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 64130 22342
Ensembl ENSG00000104863 ENSMUSG00000003872
UniProt Q9HAP6 O88951
RefSeq (mRNA) NM_022165 NM_011698
RefSeq (protein) NP_071448 NP_035828
Location (UCSC) Chr 19:
49.62 – 49.62 Mb
Chr 7:
45.37 – 45.37 Mb
PubMed search [1] [2]

Lin-7 homolog B is a protein that in humans is encoded by the LIN7B gene.[1][2]

Interactions[edit]

LIN7B has been shown to interact with:

References[edit]

  1. ^ a b Jo K, Derin R, Li M, Bredt D (Jun 1999). "Characterization of MALS/Velis-1, -2, and -3: a family of mammalian LIN-7 homologs enriched at brain synapses in association with the postsynaptic density-95/NMDA receptor postsynaptic complex". J Neurosci 19 (11): 4189–99. PMID 10341223. 
  2. ^ "Entrez Gene: LIN7B lin-7 homolog B (C. elegans)". 
  3. ^ Hruska-Hageman A, Benson C, Leonard A, Price M, Welsh M (Nov 2004). "PSD-95 and Lin-7b interact with acid-sensing ion channel-3 and have opposite effects on H+- gated current". J. Biol. Chem. 279 (45): 46962–8. doi:10.1074/jbc.M405874200. PMID 15317815. 
  4. ^ Leonoudakis D, Conti L, Anderson S, Radeke C, McGuire L, Adams M et al. (May 2004). "Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins". J. Biol. Chem. 279 (21): 22331–46. doi:10.1074/jbc.M400285200. PMID 15024025. 
  5. ^ Leonoudakis D, Conti L, Radeke C, McGuire L, Vandenberg C (Apr 2004). "A multiprotein trafficking complex composed of SAP97, CASK, Veli, and Mint1 is associated with inward rectifier Kir2 potassium channels". J. Biol. Chem. 279 (18): 19051–63. doi:10.1074/jbc.M400284200. PMID 14960569. 
  6. ^ Olsen O, Liu H, Wade J, Merot J, Welling P (Jan 2002). "Basolateral membrane expression of the Kir 2.3 channel is coordinated by PDZ interaction with Lin-7/CASK complex". Am. J. Physiol., Cell Physiol. 282 (1): C183–95. doi:10.1152/ajpcell.00249.2001. PMID 11742811. 

Further reading[edit]

  • Butz S, Okamoto M, Südhof T (1998). "A tripartite protein complex with the potential to couple synaptic vesicle exocytosis to cell adhesion in brain.". Cell 94 (6): 773–82. doi:10.1016/S0092-8674(00)81736-5. PMID 9753324. 
  • Olsen O, Liu H, Wade J, Merot J, Welling P (2002). "Basolateral membrane expression of the Kir 2.3 channel is coordinated by PDZ interaction with Lin-7/CASK complex.". Am. J. Physiol., Cell Physiol. 282 (1): C183–95. doi:10.1152/ajpcell.00249.2001. PMID 11742811. 
  • Coussen F, Normand E, Marchal C, Costet P, Choquet D, Lambert M et al. (2002). "Recruitment of the kainate receptor subunit glutamate receptor 6 by cadherin/catenin complexes.". J. Neurosci. 22 (15): 6426–36. PMID 12151522. 
  • Hori K, Konno D, Maruoka H, Sobue K (2003). "MALS is a binding partner of IRSp53 at cell-cell contacts.". FEBS Lett. 554 (1-2): 30–4. doi:10.1016/S0014-5793(03)01074-3. PMID 14596909. 
  • Leonoudakis D, Conti L, Radeke C, McGuire L, Vandenberg C (2004). "A multiprotein trafficking complex composed of SAP97, CASK, Veli, and Mint1 is associated with inward rectifier Kir2 potassium channels.". J. Biol. Chem. 279 (18): 19051–63. doi:10.1074/jbc.M400284200. PMID 14960569. 
  • Leonoudakis D, Conti L, Anderson S, Radeke C, McGuire L, Adams M et al. (2004). "Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins.". J. Biol. Chem. 279 (21): 22331–46. doi:10.1074/jbc.M400285200. PMID 15024025. 
  • Hruska-Hageman A, Benson C, Leonard A, Price M, Welsh M (2004). "PSD-95 and Lin-7b interact with acid-sensing ion channel-3 and have opposite effects on H+- gated current.". J. Biol. Chem. 279 (45): 46962–8. doi:10.1074/jbc.M405874200. PMID 15317815. 
  • Okuhira K, Fitzgerald M, Sarracino D, Manning J, Bell S, Goss J et al. (2006). "Purification of ATP-binding cassette transporter A1 and associated binding proteins reveals the importance of beta1-syntrophin in cholesterol efflux.". J. Biol. Chem. 280 (47): 39653–64. doi:10.1074/jbc.M510187200. PMID 16192269. 
  • Kawai S, Fukuda C, Mukai T, Murata K (2006). "MJ0917 in archaeon Methanococcus jannaschii is a novel NADP phosphatase/NAD kinase.". J. Biol. Chem. 280 (47): 39200–7. doi:10.1074/jbc.M506426200. PMID 16192277. 
  • Li Z, Benard O, Margolskee R (2006). "Ggamma13 interacts with PDZ domain-containing proteins.". J. Biol. Chem. 281 (16): 11066–73. doi:10.1074/jbc.M600113200. PMID 16473877. 
  • Sudo K, Ito H, Iwamoto I, Morishita R, Asano T, Nagata K (2007). "Identification of a cell polarity-related protein, Lin-7B, as a binding partner for a Rho effector, Rhotekin, and their possible interaction in neurons.". Neurosci. Res. 56 (4): 347–55. doi:10.1016/j.neures.2006.08.003. PMID 16979770.