LIN7B

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Lin-7 homolog B (C. elegans)
Protein LIN7B PDB 1y74.png
PDB rendering based on 1y74.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols LIN7B ; LIN-7B; MALS-2; MALS2; VELI2
External IDs OMIM612331 MGI1330858 HomoloGene22648 GeneCards: LIN7B Gene
RNA expression pattern
PBB GE LIN7B 219760 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 64130 22342
Ensembl ENSG00000104863 ENSMUSG00000003872
UniProt Q9HAP6 O88951
RefSeq (mRNA) NM_022165 NM_011698
RefSeq (protein) NP_071448 NP_035828
Location (UCSC) Chr 19:
49.62 – 49.62 Mb
Chr 7:
45.37 – 45.37 Mb
PubMed search [1] [2]

Lin-7 homolog B is a protein that in humans is encoded by the LIN7B gene.[1][2]

Interactions[edit]

LIN7B has been shown to interact with KCNJ4,[3] GRIN2B,[1] KCNJ12[4][5] and ACCN3.[6]

References[edit]

  1. ^ a b Jo K, Derin R, Li M, Bredt DS (Jun 1999). "Characterization of MALS/Velis-1, -2, and -3: a family of mammalian LIN-7 homologs enriched at brain synapses in association with the postsynaptic density-95/NMDA receptor postsynaptic complex". J Neurosci 19 (11): 4189–99. PMID 10341223. 
  2. ^ "Entrez Gene: LIN7B lin-7 homolog B (C. elegans)". 
  3. ^ Olsen, Olav; Liu Hui; Wade James B; Merot Jean; Welling Paul A (Jan 2002). "Basolateral membrane expression of the Kir 2.3 channel is coordinated by PDZ interaction with Lin-7/CASK complex". Am. J. Physiol., Cell Physiol. (United States) 282 (1): C183–95. doi:10.1152/ajpcell.00249.2001. ISSN 0363-6143. PMID 11742811. 
  4. ^ Leonoudakis, Dmitri; Conti Lisa R; Anderson Scott; Radeke Carolyn M; McGuire Leah M M; Adams Marvin E; Froehner Stanley C; Yates John R; Vandenberg Carol A (May 2004). "Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins". J. Biol. Chem. (United States) 279 (21): 22331–46. doi:10.1074/jbc.M400285200. ISSN 0021-9258. PMID 15024025. 
  5. ^ Leonoudakis, Dmitri; Conti Lisa R; Radeke Carolyn M; McGuire Leah M M; Vandenberg Carol A (Apr 2004). "A multiprotein trafficking complex composed of SAP97, CASK, Veli, and Mint1 is associated with inward rectifier Kir2 potassium channels". J. Biol. Chem. (United States) 279 (18): 19051–63. doi:10.1074/jbc.M400284200. ISSN 0021-9258. PMID 14960569. 
  6. ^ Hruska-Hageman, Alesia M; Benson Christopher J; Leonard A Soren; Price Margaret P; Welsh Michael J (Nov 2004). "PSD-95 and Lin-7b interact with acid-sensing ion channel-3 and have opposite effects on H+- gated current". J. Biol. Chem. (United States) 279 (45): 46962–8. doi:10.1074/jbc.M405874200. ISSN 0021-9258. PMID 15317815. 

Further reading[edit]