From Wikipedia, the free encyclopedia
Jump to: navigation, search
Lin-7 homolog C (C. elegans)
Protein LIN7C PDB 2dkr.png
PDB rendering based on 2dkr.
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols LIN7C ; LIN-7-C; LIN-7C; MALS-3; MALS3; VELI3
External IDs OMIM612332 MGI1330839 HomoloGene22649 GeneCards: LIN7C Gene
RNA expression pattern
PBB GE LIN7C 219399 at tn.png
PBB GE LIN7C 221568 s at tn.png
More reference expression data
Species Human Mouse
Entrez 55327 22343
Ensembl ENSG00000148943 ENSMUSG00000027162
UniProt Q9NUP9 O88952
RefSeq (mRNA) NM_018362 NM_011699
RefSeq (protein) NP_060832 NP_035829
Location (UCSC) Chr 11:
27.52 – 27.53 Mb
Chr 2:
109.89 – 109.9 Mb
PubMed search [1] [2]

Lin-7 homolog C is a protein that in humans is encoded by the LIN7C gene.[1][2]


LIN7C has been shown to interact with KCNJ4,[3][4] KCNJ12[3][4] and DLG1.[4]


  1. ^ Jo K, Derin R, Li M, Bredt DS (Jun 1999). "Characterization of MALS/Velis-1, -2, and -3: a family of mammalian LIN-7 homologs enriched at brain synapses in association with the postsynaptic density-95/NMDA receptor postsynaptic complex". J Neurosci 19 (11): 4189–99. PMID 10341223. 
  2. ^ "Entrez Gene: LIN7C lin-7 homolog C (C. elegans)". 
  3. ^ a b Leonoudakis, Dmitri; Conti Lisa R; Anderson Scott; Radeke Carolyn M; McGuire Leah M M; Adams Marvin E; Froehner Stanley C; Yates John R; Vandenberg Carol A (May 2004). "Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins". J. Biol. Chem. (United States) 279 (21): 22331–46. doi:10.1074/jbc.M400285200. ISSN 0021-9258. PMID 15024025. 
  4. ^ a b c Leonoudakis, Dmitri; Conti Lisa R; Radeke Carolyn M; McGuire Leah M M; Vandenberg Carol A (Apr 2004). "A multiprotein trafficking complex composed of SAP97, CASK, Veli, and Mint1 is associated with inward rectifier Kir2 potassium channels". J. Biol. Chem. (United States) 279 (18): 19051–63. doi:10.1074/jbc.M400284200. ISSN 0021-9258. PMID 14960569. 

Further reading[edit]