LIN7C

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Lin-7 homolog C (C. elegans)
Protein LIN7C PDB 2dkr.png
PDB rendering based on 2dkr.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols LIN7C ; LIN-7-C; LIN-7C; MALS-3; MALS3; VELI3
External IDs OMIM612332 MGI1330839 HomoloGene22649 GeneCards: LIN7C Gene
RNA expression pattern
PBB GE LIN7C 219399 at tn.png
PBB GE LIN7C 221568 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 55327 22343
Ensembl ENSG00000148943 ENSMUSG00000027162
UniProt Q9NUP9 O88952
RefSeq (mRNA) NM_018362 NM_011699
RefSeq (protein) NP_060832 NP_035829
Location (UCSC) Chr 11:
27.52 – 27.53 Mb
Chr 2:
109.89 – 109.9 Mb
PubMed search [1] [2]

Lin-7 homolog C is a protein that in humans is encoded by the LIN7C gene.[1][2]

Interactions[edit]

LIN7C has been shown to interact with:

References[edit]

  1. ^ Jo K, Derin R, Li M, Bredt D (Jun 1999). "Characterization of MALS/Velis-1, -2, and -3: a family of mammalian LIN-7 homologs enriched at brain synapses in association with the postsynaptic density-95/NMDA receptor postsynaptic complex". J Neurosci 19 (11): 4189–99. PMID 10341223. 
  2. ^ "Entrez Gene: LIN7C lin-7 homolog C (C. elegans)". 
  3. ^ a b c Leonoudakis D, Conti L, Radeke C, McGuire L, Vandenberg C (Apr 2004). "A multiprotein trafficking complex composed of SAP97, CASK, Veli, and Mint1 is associated with inward rectifier Kir2 potassium channels". J. Biol. Chem. 279 (18): 19051–63. doi:10.1074/jbc.M400284200. PMID 14960569. 
  4. ^ a b Leonoudakis D, Conti L, Anderson S, Radeke C, McGuire L, Adams M et al. (May 2004). "Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins". J. Biol. Chem. 279 (21): 22331–46. doi:10.1074/jbc.M400285200. PMID 15024025. 

Further reading[edit]

  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298. 
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149. 
  • Bécamel C, Alonso G, Galéotti N, Demey E, Jouin P, Ullmer C et al. (2002). "Synaptic multiprotein complexes associated with 5-HT(2C) receptors: a proteomic approach". EMBO J. 21 (10): 2332–42. doi:10.1093/emboj/21.10.2332. PMC 126011. PMID 12006486. 
  • Hori K, Konno D, Maruoka H, Sobue K (2003). "MALS is a binding partner of IRSp53 at cell-cell contacts". FEBS Lett. 554 (1–2): 30–4. doi:10.1016/S0014-5793(03)01074-3. PMID 14596909. 
  • Leonoudakis D, Conti L, Radeke C, McGuire L, Vandenberg C (2004). "A multiprotein trafficking complex composed of SAP97, CASK, Veli, and Mint1 is associated with inward rectifier Kir2 potassium channels". J. Biol. Chem. 279 (18): 19051–63. doi:10.1074/jbc.M400284200. PMID 14960569. 
  • Leonoudakis D, Conti L, Anderson S, Radeke C, McGuire L, Adams M et al. (2004). "Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins". J. Biol. Chem. 279 (21): 22331–46. doi:10.1074/jbc.M400285200. PMID 15024025. 
  • Petrosky K, Ou H, Löhr F, Dötsch V, Lim W (2006). "A general model for preferential hetero-oligomerization of LIN-2/7 domains: mechanism underlying directed assembly of supramolecular signaling complexes". J. Biol. Chem. 280 (46): 38528–36. doi:10.1074/jbc.M506536200. PMID 16147993. 
  • Mendes C, Gomes D, Thompson M, Souto N, Goes T, Goes A et al. (2006). "The type III inositol 1,4,5-trisphosphate receptor preferentially transmits apoptotic Ca2+ signals into mitochondria". J. Biol. Chem. 280 (49): 40892–900. doi:10.1074/jbc.M506623200. PMID 16192275. 
  • Bohl J, Brimer N, Lyons C, Vande Pol S (2007). "The stardust family protein MPP7 forms a tripartite complex with LIN7 and DLG1 that regulates the stability and localization of DLG1 to cell junctions". J. Biol. Chem. 282 (13): 9392–400. doi:10.1074/jbc.M610002200. PMID 17237226. 
  • Onda T, Uzawa K, Nakashima D, Saito K, Iwadate Y, Seki N et al. (2007). "Lin-7C/VELI3/MALS-3: an essential component in metastasis of human squamous cell carcinoma". Cancer Res. 67 (20): 9643–8. doi:10.1158/0008-5472.CAN-07-1911. PMID 17942893.