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PubChem 9906198
ChemSpider 8081850
Jmol-3D images Image 1
Molecular formula C22H35NO2
Molar mass 345.52 g mol−1
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
Infobox references

LY-255582 is a phenylpiperidine opioid antagonist. It has been shown to reduce ethanol consumption in experiments carried out on rats.[1] It has also been shown to reduce food and water consumption in rats.[2]


  1. ^ Dhaher R, et al. (Feb 2012). "Effects of naltrexone and LY255582 on ethanol maintenance, seeking, and relapse responding by alcohol-preferring (P) rats.". Alcohol. 46 (1): 17–27. doi:10.1016/j.alcohol.2011.08.011. 
  2. ^ Shaw WN, et al. (Jun 1991). "The effect of the opioid antagonist LY255582 on body weight of the obese Zucker rat.". Int J Obes. 15 (6): 387–95. PMID 1653188.