Enzastaurin

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Enzastaurin
Enzastaurin.png
Identifiers
CAS number 170364-57-5 YesY
PubChem 176167
ChemSpider 153463 N
ChEMBL CHEMBL300138 N
Jmol-3D images Image 1
Properties
Molecular formula C32H29N5O2
Molar mass 515.60 g mol−1
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N (verify) (what is: YesY/N?)
Infobox references

Enzastaurin is a synthetic bisindolylmaleimide with potential antineoplastic activity. Binding to the ATP-binding site, enzastaurin selectively inhibits protein kinase C beta, an enzyme involved in the induction of vascular endothelial growth factor (VEGF)-stimulated neo-angiogenesis. This agent may decrease tumor blood supply, preventing growth.

In 2013 it failed a phase III clinical trial for lymphoma.[1]

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