The song has distinctive instrumentation, including an oboe solo, liberal use of the mellotron's famous "three violins" tape set, and much processing of the other instruments by Brian Eno via his Electronic Music StudiosVCS3synthesizer and tape echo. The sound in the start of the song was created by Brian Eno, after Bryan Ferry asked him to produce something reminiscent of the Lunar Landing.
Lyrically, it presents Ferry as a Casanova-style seducer of women, whilst being simultaneously enraptured by them. Another interpretation is that the Ladytron is a female robot (hence the name), being seduced by Ferry.
The Times has called Ladytron one of Roxy Music's "best loved songs."