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Lampricide is a chemical which is designed to target the larvae of lampreys in river systems before their recruitment as parasitic adults. TFM (3-trifluoromethyl-4-nitrophenol) is one such chemical. [1] While effective in that it typically does not harm other fish due to the evolutionary relationship between true fish and lampreys[citation needed], lampricides can be problematic for amphibians such as mudpuppies (genus Necturus) which often share the same habitats. Also, some more "primitive" species of fish, such as the sturgeon in the Great Lakes are sensitive to chemicals such as TFM.

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