Lanthanum carbonate

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Lanthanum carbonate
Identifiers
CAS number 54451-24-0 YesY
PubChem 168924
ChemSpider 147758 YesY
ChEMBL CHEMBL1201031 N
ATC code V03AE03
Jmol-3D images Image 1
Properties
Molecular formula La2(CO3)3
Molar mass 457.838 g/mol
Appearance White powder, hygroscopic
Density 2.6–2.7 g/cm3
Melting point decomposes
Solubility in water negligible
Solubility soluble in acids
Related compounds
Other anions Lanthanum(III) oxide
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N (verify) (what is: YesY/N?)
Infobox references

Lanthanum carbonate, La2(CO3)3, is the salt formed by lanthanum(III) cations and carbonate anions. It is an ore of lanthanum metal, along with monazite.

Chemistry[edit]

Lanthanum carbonate is used as a starting material in lanthanum chemistry, particularly in forming mixed oxides, for example

Human and veterinary medicine[edit]

Lanthanum carbonate is used in medicine as a phosphate binder.[1] As a medication it is sold under the trade name Fosrenol by the pharmaceutical company Shire Pharmaceuticals. Fosrenol is the largest of all pills filled in community pharmacies. Sometimes patients forget that fosrenol is not swallowed whole, but instead should be chewed. This has led to severe choking. It is prescribed for the treatment of hyperphosphatemia, primarily in patients with chronic kidney disease. It is taken with meals and binds to dietary phosphate, preventing phosphate from being absorbed by the intestine. For cats suffering from hyperphosphatemia it is available under the trade name Renalzin by Bayer Animal Health.[2]

However, when lanthanum carbonate is used for treating hyperphosphatemia, its side effects, namely myalgia, muscular cramping, and peripheral edema, should be clinically monitored.[3]

Other applications[edit]

Lanthanum carbonate is also used for the tinting of glass, for water treatment, or as a catalyst for hydrocarbon cracking.

References[edit]

  1. ^ Editorial Staff (December 2004). "Lanthanum Carbonate". All Micromedex Systems. Micromedex, Inc. Archived from the original on 2007-09-14. Retrieved 2007-11-25. 
  2. ^ Bayer Animal Health (26 September 2008). "Bayer Animal Health launches Renalzin for Cats" (PDF). Retrieved 2008-09-30. 
  3. ^ http://www.ncbi.nlm.nih.gov/pubmed?term=N%20Engl%20J%20Med%202010%3B362%3A1312-24.

External links[edit]