Lanugo

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Lanugo
Lanugo.png
ICD-10 Q84.2
ICD-9 757.4
DiseasesDB 30821

Lanugo (/la·nu·go/,[1] from Latin lana "wool") is very fine, soft, and usually unpigmented, downy hair as can be found on the body of a fetus or newborn baby. It is the first hair to be produced by the fetal hair follicles, and it usually appears on the fetus at about 5 months of gestation. It is normally shed before birth, around 7 or 8 months of gestation but is sometimes present at birth and disappears on its own within a few days or weeks.[2]

Lanugo hair will be shed by three to four months after birth. It is replaced by hair covering the same surfaces called vellus hair, but this hair is finer and more difficult to see. The more visible hair that continues into adulthood is called terminal hair. This forms in specific areas and is hormone dependent.[3]

Occurrence[edit]

In humans[edit]

Fetal development[edit]

During human development, the lanugo grows on fetuses as a normal part of gestation, but is usually shed and replaced by vellus hair at about 33 to 36 weeks of gestational age. As the lanugo is shed from the skin, it is normal for the developing fetus to consume the hair with the fluid, since it drinks from the amniotic fluid and urinates it back into its environment. Subsequently, the lanugo contributes to the newborn baby's meconium. The presence of lanugo in newborns is a sign of premature birth.

Lanugo functions as an anchor to hold the vernix caseosa on the skin. This combination with vernix caseosa protects the delicate fetal skin from damage from the amniotic fluid.[4] The vernix caseosa also helps to transition the fetus to life outside the womb. It is thought to provide lubrication for birth and it is shown to effect theromoregulation, water loss, and innate immunity. Without the lanugo to anchor the vernix caseosa these functions would be lost.[5]

Malnutrition[edit]

Lanugo can be observed in malnourished patients, including those with eating disorders. When found along with other physical symptoms, for example, lanugo can help a physician make a diagnosis of anorexia nervosa or bulimia nervosa.[6]

Teratoma[edit]

It is often found in teratomas (congenital tumours).

In animals[edit]

Lanugo is also common on other animals. For example, seals[7] and elephants[8][9][10] are often born with a covering of lanugo.

Fetal whales, like humans and all other primates, also have lanugo.

References[edit]

  1. ^ "Lanugo : definition". TheFreeDictionary. Retrieved 17 February 2013. 
  2. ^ "Definition of Lanugo". MedicineNet: medterms medical dictionary. Retrieved 17 February 2013. 
  3. ^ "What is lanugo?". SheKnows. Retrieved 17 February 2013. 
  4. ^ Moore, Keith L (Dec 19, 2011). The Developing Human: Clinically Oriented Embryology. Elsevier. p. 98. ISBN 1437720021. 
  5. ^ Singh, G; Archana (2008). "UNRAVELING THE MYSTERY OF VERNIX CASEOSA". Indian Journal of Dermatology 53 (2): 54–60. doi:10.4103/0019-5154.41645. 
  6. ^ "Treating Eating Disorders in Primary Care", P.M. Williams, et al, American Family Physician, Vol 77 (2): January 15, 2008
  7. ^ Androukaki, E.; Fatsea, E., 't Hart, L., Osterhaus, A.D.M.E., Tounta, E. and Kotomatas, S. (May 2002). "Growth and Development of Mediterranean Monk Seal Pups during Rehabilitation". Monachus Science Posters 5 (1): This poster was presented at the 16th ECS (European Cetacean Society) Conference, "Marine Mammal Health: from Individuals to Populations", 7–11 April 2002, Liege, Belgium. Retrieved 13 April 2013. 
  8. ^ Ecology of the Asian Elephant in Lowland Dry Zone Habitats of the Mahaweli River Basin, Sri Lanka Natarajan Ishwaran Journal of Tropical Ecology, Vol. 9, No. 2 (May, 1993), pp. 169-182
  9. ^ The Hair, Paul MacKenzie, Elephant Information Repository website
  10. ^ Elephant Hair, Elephant Anatomy, Animal Corner website

External links[edit]