At Northwestern University, Larry Brody majored in English and wrote dozens of short stories, poetry and essays. As an avid science fiction fan, he started writing in the genre, and by the time he graduated he was selling stories to The Magazine of Fantasy & Science Fiction. After graduation he went law school but quit after one year and enrolled at the University of Iowa, for its Writers Workshop. During that first school year, at the age of 22, Brody sold his first novel. In 1968, he moved to Los Angeles to pursue a career as a screenwriter.
Once in Los Angeles, Brody wrote scripts for cop shows. He worked on Ironside, Hawaii Five-O, and became executive story consultant for The Streets of San Francisco and Police Story. Since then, he has written for dozens of television series, including The New Land.
In the summer of 2002 Brody moved to St. Joe, Arkansas, to establish the Cloud Creek Institute for the Arts. Brody also maintains the TVWriter.com website.