Kirk is best known to fans as Lisa Picard from the 2000 movie Lisa Picard is Famous having co-written the story with friend Nat DeWolf.
A graduate of the University of Kansas in Lawrence, Kansas, Kirk most recently played Shelia Denning in the made for TV movie, A Boyfriend for Christmas as well as a guest on the television series House. Laura has a Bacon number of 2. She was in Lisa Picard is Famous with Sandra Bullock who was in Loverboy with Bacon.
- At First Sight (1999) as Betsy Ernst
- Lisa Picard is Famous (2000) as Lisa Picard
- The Time Machine (2002) as Flower Seller
- Murder Without Conviction (2004) as Alberta Talley
- A Boyfriend for Christmas (2004) as Shelia Denning
- Bunker Hill (2008) as Hallie
- The Only Good Indian (2009) as Miss Harris