Pritchard was born in 1977 in Orlando, Florida. She trained as a ballet dancer and danced from age two until she was twenty years old. She toured with the Nutcracker and auditioned for ABT and Miami ballet theater. Pritchard began taking improv classes in 1991 in Orlando, Florida at SAK theatre, with Wayne Brady as her first improv teacher. She was hired by Disney in 1995 and she appeared in Equity shows at EPCOT.
In 2002, Lauren joined the main company of ComedySportz Los Angeles. In addition to improvising, she also currently directs the organization's Sunday Team.
Pritchard joined the cast of MADtv in 2008 as a feature player for the show's final season (season 14; 2008-2009). Pritchard had no recurring characters, but she was known for her impressions of Candy Crowley, Jo Frost, and Queen Elizabeth II.