Stein spent a number of years living in Paris with his sister. In 1914, the two split due to Leo's resentment of Gertrude's infatuation with Alice B. Toklas, whom he described as "a kind of abnormal vampire". Stein returned to America to work as a journalist but eventually settled near Florence, Italy, with his long-time love interest, Nina Auzias. They eventually married in 1921.
Stein died of cancer in 1947 in Florence. Auzias committed suicide two years later.