Leu-enkephalin

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Leu-enkephalin
Leu-enkaphalin.png
Identifiers
CAS number 58822-25-6 YesY
PubChem 461776
ChemSpider 406229 N
ChEMBL CHEMBL8234 N
IUPHAR ligand 1613
Jmol-3D images Image 1
Properties
Molecular formula C28H37N5O7
Molar mass 555.62268 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N (verify) (what is: YesY/N?)
Infobox references

Leu-enkephalin is an endogenous opioid peptide neurotransmitter with the amino acid sequence Tyr-Gly-Gly-Phe-Leu that is found naturally in the brains of many animals, including humans. It is one of the two forms of enkephalin; the other is met-enkephalin. The tyrosine residue at position 1 is thought to be analogous to the 3-hydroxyl group on morphine. Leu-enkephalin has agonistic actions at both the μ- and δ-opioid receptors, with significantly greater preference for the latter. It has little to no effect on the κ-opioid receptor.

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