Leukotriene A4

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Leukotriene A4
Identifiers
CAS number 72059-45-1
PubChem 5280383
MeSH Leukotriene+A4
Properties
Molecular formula C20H30O3
Molar mass 318.45 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Leukotriene A4 is a leukotriene.

Leukotriene A4 hydrolase converts it to Leukotriene B4.

Eicosanoid synthesis. (Leukotrienes at right.)
v • d • e
Autacoids, unsaturated fatty acids: Eicosanoids
Precursor
Prostanoids
Precursor
Active
D/J
E/F
I
A2 · B2
Leukotrienes (LT)
Precursor
Initial
A4 · B4
C4 · D4 · E4
Nonclassic
By function

bronchoconstriction (PGF2α, TXA2, LTC4, LTD4, LTE4)

vasoconstriction (PGF2α, TXA2, TXB2) · vasodilation (PGE2, PGI2, LTC4, LTD4, LTE4)

platelets: induce (TXA2) inhibit (PGD2, PGI2) · leukocytes: induce (TXA2, LTB4) inhibit (PGD2, PGE2)

labor stimulation: (PGE2 (Dinoprostone), PGF2α (Dinoprost))
see also enzymes


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