Leukotriene D4

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Leukotriene D4
Leukotriene D4.svg
CAS number 73836-78-9 YesY
PubChem 5280878
MeSH Leukotriene+D4
Jmol-3D images Image 1
Molecular formula C25H40N2O6S
Molar mass 496.661 g/mol
Except where noted otherwise, data are given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
 N (verify) (what is: YesY/N?)
Infobox references

Leukotriene D4 (LTD-4) is one of the leukotrienes. Its functions in the body are bronchoconstriction, vasoconstriction, contraction of smooth muscle, and increasing vascular permeability. LTD-4 is released by basophils. Other leukotrienes that function in a similar manner are leukotrienes C4 and E4. Pharmacological agents that inhibit the function of these leukotrienes are leukotriene receptor antagonists (e.g. Zafirlukast, montelukast) and are useful for asthmatic individuals.

Eicosanoid synthesis. (Leukotrienes at right.)