Leukotriene D4

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Leukotriene D4
Leukotriene D4.svg
Identifiers
CAS number 73836-78-9 YesY
ChEBI CHEBI:28666 N
ChEMBL ChEMBL288943 N
Jmol-3D images Image
MeSH Leukotriene+D4
PubChem 5280878
Properties
C25H40N2O6S
Molar mass 496.661 g/mol
Except where noted otherwise, data is given for materials in their standard state (at 25 °C (77 °F), 100 kPa)
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Infobox references

Leukotriene D4 (LTD-4) is one of the leukotrienes. Its function main in the body is to induce the contraction of smooth muscle, resulting in bronchoconstriction and vasoconstriction. It also increases vascular permeability. LTD-4 is released by basophils. Other leukotrienes that function in a similar manner are leukotrienes C4 and E4. Pharmacological agents that inhibit the function of these leukotrienes are leukotriene receptor antagonists (e.g. Zafirlukast, montelukast) and are useful for asthmatic individuals.

Eicosanoid synthesis. (Leukotrienes at right.)